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Microsatellite instability in gastric cancer

✍ Scribed by Wirtz, H.-Ch.; Müiler, W.; Noguchi, T.; Scheven, M.; Rüschoff, J.; Gabbert, H.E.


Book ID
123332481
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
263 KB
Volume
33
Category
Article
ISSN
0959-8049

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Forty-three sporadic gastric cancers were analyzed with regard to whether mutations of simple repeated sequences in the transforming growth factor fi type II receptor ( T p -I / ) gene are associated with microsatellite instability (MSI) and gastric carcinogenesis. In 12 ofthe 43 cancers (28%), MSI