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Microsatellite Instability and Somatic Mutations in Endometrial Carcinomas

✍ Scribed by Takako Sakamoto; Takayuki Murase; Hironobu Urushibata; Kiyoko Kato; Hiroyuki Takada; Toshiro Imamura; Hiroyuki Mori; Norio Wake

Book ID
112247496
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
189 KB
Volume
71
Category
Article
ISSN
0090-8258

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## Background: Microsatellite instability (mi) is a frequent occurrence in endometrioid carcinoma of the endometrium (ec). several genes known to contain mononucleotide short tracts in their coding sequences (tgf-beta rii, igfiir, bax, hmsh6, and hmsh3) are likely targets for mutations in these tum