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Microglial Reaction in MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) Induced Parkinson's Disease Mice Model

✍ Scribed by Anna Członkowska; Małgorzata Kohutnicka; Iwona Kurkowska-Jastrzębska; Andrzej Członkowski

Book ID
115641888
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
756 KB
Volume
5
Category
Article
ISSN
1055-8330

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## Abstract In 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP) models of Parkinson's disease (PD), dopaminergic (DA) neurons have been shown to die by apoptosis. Moreover, recent postmortem and in vitro results have indicated that apoptotic cell death induced by 1‐methyl‐4‐phenylpyridinium (MPP