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Dipyridamole potentiates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced experimental Parkinsonism in mice

✍ Scribed by Mohammad Tariq; Haseeb A. Khan; Khalaf Al Moutaery; Saleh Al Deeb


Book ID
117755414
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
959 KB
Volume
4
Category
Article
ISSN
1353-8020

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## Abstract In 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP) models of Parkinson's disease (PD), dopaminergic (DA) neurons have been shown to die by apoptosis. Moreover, recent postmortem and in vitro results have indicated that apoptotic cell death induced by 1‐methyl‐4‐phenylpyridinium (MPP