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Microfluidic technology: An economical and versatile approach for the synthesis of O-(2-[18F]fluoroethyl)-l-tyrosine ([18F]FET)

✍ Scribed by Vincent Bouvet; Melinda Wuest; Pui-Hang Tam; Monica Wang; Frank Wuest


Book ID
113496639
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
630 KB
Volume
22
Category
Article
ISSN
0960-894X

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## Abstract A slightly modified automated commercial synthesis system for preparation of __O__‐(2‐[^18^F]fluoroethyl)‐l‐tyrosine (FET), an amino acid tracer for tumor imaging with positron emission tomography, is described. Direct nucleophilic fluorination of [^18^F]fluoride with 1,2‐di(4‐methylphe