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Microduplications At 22q11.21 are Associated with Classic Bladder Exstrophy

✍ Scribed by Wolfgang H. Rösch; Markus Draaken; Michael Ludwig; Heiko Reutter; Charlotte Schramm; Enrika Bartels; Thomas M. Boemers; Annette Schröder; Raimund Stein; Markus M. Nöthen; Anne-Karoline Ebert


Book ID
116693921
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
35 KB
Volume
6
Category
Article
ISSN
1477-5131

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This study has analysed 65 urothelial carcinomas for allelic imbalance at 22 loci of chromosome 5 and has determined three regions of interest. A commonly duplicated region was mapped to chromosome 5p between loci D5S1473 and D5S819, one region of deletion to chromosome 5q22±23 between loci D5S2055