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Polymorphisms in tumour necrosis factor (TNF) are associated with risk of bladder cancer and grade of tumour at presentation

โœ Scribed by Marsh, H P; Haldar, N A; Bunce, M; Marshall, S E; le Monier, K; Winsey, S L; Christodoulos, K; Cranston, D; Welsh, K I; Harris, A L


Book ID
109997696
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
102 KB
Volume
89
Category
Article
ISSN
0007-0920

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## Abstract Tumour necrosis factor alpha (TNF) mRNA is detected in the macrophage infiltrate surrounding the tumour, but the cellular/ molecular interactions leading to TNF gene expression in macrophages are unknown. The __in vitro__ system in which human blood monocytes are stimulated with human c