Microchip capillary electrophoresis for frontal analysis of free bilirubin and study of its interaction with human serum albumin
β Scribed by Zhou Nie; Ying Sing Fung
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 346 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0173-0835
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Capillary electrophoresis frontal analysis was applied to 12 low molecular weight compounds including 8 drug substances displaying a range of different properties with respect to binding affinity, binding location, structure, lipophilicity, charge at physiological pH, and electrophoretic mobility. I
An error introduced in the page setting stage after final proofs were checked resulted in a changeover of the images in panels A and B of Fig. 4. The correct version of Fig. 4A and B is as follows:
Capillary electrophoresis (CE) is a promising technique for assessment of free bilirubin and its interaction with albumin, as it requires only a small sample volume and provides a rapid and efficient separation of free bilirubin from its albumin-bound complex in a one-phase system. In order to maint