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Microbial transformation of racemic hydantoins to D-amino acids

✍ Scribed by R. Olivieri; E. Fascetti; L. Angelini; L. Degen

Publisher: John Wiley and Sons
Year: 1981
Tongue: English
Weight: 419 KB
Volume: 23
Category: Article
ISSN: 0006-3592
DOI: 10.1002/bit.260231002

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✦ Synopsis

Abstract

It has been shown that resting cells of Agrobacterium radiobacter catalyze a sequence of two stereospecific hydrolytic reactions leading to the complete transformation of racemic hydantoins to D‐amino acids. This report describes some properties of this new biocatalyst and its potential application for the production of some D‐amino acids, which are used as intermediates in the preparation of semisynthetic penicillin and cephalosporins.

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