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Microbial Transformation of (+)-Androsta-1,4-Diene-3,17-Dione by Cephalosporium Aphidicola

✍ Scribed by ChoudHary, M. Iqbal; Musharraf, S. Ghulam; Shaheen, Farzana; Atta-Ur-Rahman,

Book ID
126230620
Publisher
Taylor and Francis Group
Year
2002
Tongue
English
Weight
130 KB
Volume
16
Category
Article
ISSN
1057-5634

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## Abstract A biotransformation process using __Mycobacterium__ sp was studied for androsta‐1, 4‐diene‐3,17‐dione (ADD) and androsta‐4‐ene‐3,17‐dione (AD) production from cholesterol. Cholesterol has a poor solubility in water (∼1.8 mg dm^βˆ’3^ at 25 °C), which makes it difficult to use as the substr