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Microbiological hydroxylation of androst-4-ene-3,17-dione and androsta-1,4-diene-3,17-dione

✍ Scribed by T. S. Kolyvanova; V. I. Bayunova; K. N. Gabinskaya; Yu. N. Korobova; G. S. Grinenko


Book ID
112396834
Publisher
Springer
Year
1989
Tongue
English
Weight
316 KB
Volume
23
Category
Article
ISSN
0091-150X

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## Abstract A biotransformation process using __Mycobacterium__ sp was studied for androsta‐1, 4‐diene‐3,17‐dione (ADD) and androsta‐4‐ene‐3,17‐dione (AD) production from cholesterol. Cholesterol has a poor solubility in water (∼1.8 mg dm^βˆ’3^ at 25 °C), which makes it difficult to use as the substr