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Microbial synthesis of three metabolites of a tachykinin receptor antagonist, TAK-637

✍ Scribed by Naoki Tarui; Yoshinori Ikeura; Hideaki Natsugari; Kazuo Nakahama

Book ID
118626353
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
386 KB
Volume
92
Category
Article
ISSN
1389-1723

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πŸ“œ SIMILAR VOLUMES

Microbial synthesis of a deuterium-label
Microbial synthesis of a deuterium-labelled metabolite of an NK1 receptor antagonist, TAK-637
✍ Naoki Tarui; Yoshinori Ikeura; Hideaki Natsugari; Kazuo Nakahama πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 French βš– 95 KB

## Abstract Microbial conversion of deuterium‐labelled TAK‐637 ((__aR,9S__)‐[10,10,11, 11‐^2^H~4~]‐7‐[3,5‐__bis__(trifluoromethyl)benzyl]‐8,9,10,11‐tetrahydro‐9‐methyl‐5‐(4‐methylphenyl)‐__7H__‐[1,4]diazocino[2,1‐__g__][1,7]naphthyridine‐6,13‐dione, **1**) was carried out using __Streptomyces subru