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Microbial engineering of dehydro-amino acids and lanthionines in non-lantibiotic peptides

✍ Scribed by Gert N. Moll; Anneke Kuipers; Rick Rink


Publisher
Springer Netherlands
Year
2010
Tongue
English
Weight
261 KB
Volume
97
Category
Article
ISSN
0003-6072

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The dehydro-residue containing peptides N-Ac-dehydro-Phe-L-Leu-OCH3 ( I ) and N-Acdehydro-Phe-NorVal-OCH, (11) were synthesized by the usual workup procedures. The peptides crystallize from their solutions in methanol in space group P6,: ( I ) a = b = 12.528(2) A, c = 21.653(5) A; (11) a = b = 12.53