Mevinic acids and analogues: preparation of a key chiral intermediate
β Scribed by Yuh-Lin Yang; J.R. Flack
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- French
- Weight
- 213 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
The preparation of methyl 3-O-tert-butyldiphenylsilyl-2,4-dideoxy-B-D-erythrohexopyranoside, a key chiral intermediate for mevinic acids, and its elaboration into four mevinate analogues are described.
π SIMILAR VOLUMES
Enantiomerically pure 4-amino-5,6-O-isopropylidenedioxycyclohex-2-en-1-ol, conveniently prepared by the union of O-isopropylidenedioxycyclohexadiene with camphor-based chloronitroso ester, was employed in the synthesis of versatile key intermediates toward narcissus alkaloids.
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