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Preparation and conversion of chiral O-isopropylidene-protected 4-aminocyclohexenol to various key intermediates toward narcissus alkaloids

✍ Scribed by Shanmugham Elango; Ying-Chuan Wang; Chien-Liang Cheng; Tu-Hsin Yan


Publisher
Elsevier Science
Year
2002
Tongue
French
Weight
73 KB
Volume
43
Category
Article
ISSN
0040-4039

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✦ Synopsis


Enantiomerically pure 4-amino-5,6-O-isopropylidenedioxycyclohex-2-en-1-ol, conveniently prepared by the union of O-isopropylidenedioxycyclohexadiene with camphor-based chloronitroso ester, was employed in the synthesis of versatile key intermediates toward narcissus alkaloids.