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Methylation of the prominin 1 TATA-less main promoters and tissue specificity of their transcript content

✍ Scribed by Victor V. Pleshkan; Tatyana V. Vinogradova; Eugene D. Sverdlov


Book ID
116272481
Publisher
Elsevier
Year
2008
Tongue
English
Weight
948 KB
Volume
1779
Category
Article
ISSN
1874-9399

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## Abstract Myelin basic protein (MBP) is one of the major components of the myelin sheath that insulates axons. In the central nervous system, MBP is synthesized by differentiating oligodendrocytes. The expression of MBP in oligodendrocytes is regulated mainly at the transcriptional level. The Sp1