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Synergistic Activation of the TATA-less Mouse Thymidylate Synthase Promoter by the Ets Transcription Factor GABP and Sp1

✍ Scribed by Thomas L. Rudge; Lee F. Johnson


Book ID
115604210
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
157 KB
Volume
274
Category
Article
ISSN
0014-4827

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Inactivation of MED-1 elements in the TA
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The mouse thymidylate synthase (TS) promoter is a member of a family of promoters that lack a TATA box as well as an initiator element and that initiate transcription at many sites over a broad initiation window. An element (MED-1) downstream of the initiation window of almost all promoters of this