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Methylation of gene CHFR promoter in acute leukemia cells

โœ Scribed by Gong Hui; Liu Wengli; Zhou Jianfeng; Xu Huizhen

Book ID
105624051
Publisher
Springer-Verlag
Year
2005
Tongue
Chinese
Weight
306 KB
Volume
25
Category
Article
ISSN
0510-9752

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## Abstract Chromosomal instability (CIN) is a cytogenetic hallmark of human cancers. Increasing evidence suggests that impairment of mitotic checkpoint is causally associated with CIN. CHFR is one of the mitotic checkpoint regulators and it delays chromosome condensation in response to mitotic str