In the title molecule, C 17 H 14 BrNO 4 S, the methoxycarbonyl group is almost coplanar [dihedral angle = 5.89 ( 16) ] with the indole ring system, whereas the sulfonyl-bound phenyl ring is almost orthogonal to it [dihedral angle = 88.25 (6) ]. Weak C-HÁ Á ÁO, C-HÁ Á Á andinteractions link the molec
Methyl indole-3-carboxylate
✍ Scribed by Hu, Shen-Cai ;Tan, Ren-Xiang ;Hong, Kui ;Yu, Zi-Niu ;Zhu, Hai-Liang
- Book ID
- 104484035
- Publisher
- International Union of Crystallography
- Year
- 2005
- Tongue
- English
- Weight
- 220 KB
- Volume
- 61
- Category
- Article
- ISSN
- 1600-5368
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✦ Synopsis
The title compound, C 10 H 9 NO 2 , was isolated and characterized from an EtOAc extract of marine Streptomyces sp. 060524. All atoms, except the methyl H atoms, are nearly coplanar. There is an intermolecular N-HÁ Á ÁO hydrogen bond in the crystal stucture. The compound is cytotoxic against K562 human chronic leukaemia.
📜 SIMILAR VOLUMES
In the molecule of the title compound, C 10 H 8 ClNO 2 , the indole ring system is planar. In the crystal structure, the molecules are linked by intermolecular N-HÁ Á ÁO hydrogen bonds, forming centrosymmetric dimers.