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Methotrexate-associated hepatotoxicity: retrospective analysis of 210 patients with rheumatoid arthritis

✍ Scribed by William J. Shergy; Richard P. Polisson; David S. Caldwell; John R. Rice; David S. Pisetsky; Nancy B. Allen

Book ID
117014814
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
438 KB
Volume
85
Category
Article
ISSN
1555-7162

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## Abstract ## Objective There is evidence supporting a therapeutic range for methotrexate polyglutamate (MTXGlu) concentrations in the treatment of rheumatoid arthritis (RA). Knowledge of the pharmacokinetics of MTXGlu~1–5~ is required for optimal timing of blood sampling. The aim of this study w