Pharmacokinetics of oral methotrexate in
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Judith M. Dalrymple; Lisa K. Stamp; John L. O'Donnell; Peter T. Chapman; Mei Zha
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Article
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2008
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John Wiley and Sons
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English
โ 282 KB
๐ 2 views
## Abstract ## Objective There is evidence supporting a therapeutic range for methotrexate polyglutamate (MTXGlu) concentrations in the treatment of rheumatoid arthritis (RA). Knowledge of the pharmacokinetics of MTXGlu~1โ5~ is required for optimal timing of blood sampling. The aim of this study w