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Durability of treatment with methotrexate in Venezuelan patients with rheumatoid arthritis

✍ Scribed by Gloris Sánchez; Julio S. Castro; Soham Al Snih; Luísa Pérez Blanco; María H. Esteva; Ernesto García MacGregor; Marielena González; Ysabel Granados; Francisco Marín; Alexis Rosas; Antonio Tristano; Esther Chirinos; Luís Mundaraín; Gilberto Sanoja; Guisela Zambrano-Marín; Martín A. Rodríguez

Publisher
Springer
Year
2006
Tongue
English
Weight
292 KB
Volume
27
Category
Article
ISSN
0172-8172

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Pharmacokinetics of oral methotrexate in
Pharmacokinetics of oral methotrexate in patients with rheumatoid arthritis
✍ Judith M. Dalrymple; Lisa K. Stamp; John L. O'Donnell; Peter T. Chapman; Mei Zha 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 282 KB 👁 2 views

## Abstract ## Objective There is evidence supporting a therapeutic range for methotrexate polyglutamate (MTXGlu) concentrations in the treatment of rheumatoid arthritis (RA). Knowledge of the pharmacokinetics of MTXGlu~1–5~ is required for optimal timing of blood sampling. The aim of this study w