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Methods for the Cleavage of Allylic and Propargylic C–N Bonds in Amines and Amides – Selected Alternative Applications of the 1,3-Hydrogen Shift

✍ Scribed by Stéphanie Escoubet; Stéphane Gastaldi; Michèle Bertrand


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
458 KB
Volume
2005
Category
Article
ISSN
1434-193X

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## Abstract An operationally simple and highly efficient methodology for the removal of the allyl protecting group in amides and lactams has been developed by using the commercially available bis(allyl)–ruthenium(IV) catalysts [Ru(η^3^:η^2^:η^3^‐C~12~H~18~)Cl~2~] (C~12~H~18~=dodeca‐2,6,10‐triene‐1,