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Methods for the carboxyl-terminal fluorescent labeling of peptides using solid phase peptide synthesis

✍ Scribed by Angelo P. Consalvo; Paul P. Tamburini; William Stern; Stanley D. Young

Publisher: Elsevier Science
Year: 1989
Tongue: French
Weight: 217 KB
Volume: 30
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(01)80316-6

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✦ Synopsis

Two general methods for labeling synthetic peptides with a 5-dimethylamino-1-napthalenesulfonyl idansyl) group at the C-terminal residue using solid phase peptide synthesis (SPPS) are described. Dansylated peptides are ideal substrates for fluorometric proteolytic enzyme assays.

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