A process for the extraction of sulphadiazine (SDZ) and trimethoprim (TMP) from broiler fortified tissues (plasma, lung, liver, kidney, fat, muscle, skin) was developed and a liquid chromatographic (LC) method for their determination is described. After extraction in acidic medium (pH 6.8) with ethy
Methods for the assay of chloramphenicol and two of its metabolites in broiler tissues using two liquid chromatographic methods
β Scribed by M. Dagorn; J. Manceau; B. Delepine; P. Sanders
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 460 KB
- Volume
- 275
- Category
- Article
- ISSN
- 0003-2670
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π SIMILAR VOLUMES
KEY WORDS Diltiazem Stability Plasma HPLC assay INTRODUCTION Diltiazem is a calcium antagonist which is currently used in the treatment of angina pectoris, hypertension, and supraventricular arrhythmias.'-4 At present, in our laboratory, diltiazem and six of its metabolites have been identified and
Ilb R D t I -0.8 -0.2 0.5 -0.2 0.9 V I I RDFl 0.7 0.7 -0.3 CDFl -0.5 -1.81 -1 . 1 Vlll BDFl -0.2 0.0 -0. I IX RDFI 1.1 -0.3 -0.3 X BDFl' -0.4 -0.4 -0.4 -0.2 -0. I CDI-ld -0.8 400 101 200 101 I00 97 200
## Acknowledgements The authors thank the Upjohn Co., Kalamazm, Mich.. for the generous supplies of tolbutamide. One of the authors (P. M.) gratefully acknowledges the financial support of the Delegation Generale Recherche Sciences et Techniques (Paris, France).