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A high-performance liquid chromatographic method for the simultaneous determination of nicardipine and its pyridine metabolite II in plasma

โœ Scribed by Anne T. Wu; Ian J. Massey; Stanley Kushinsky

Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
395 KB
Volume
73
Category
Article
ISSN
0022-3549

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โœฆ Synopsis

Acknowledgements

The authors thank the Upjohn Co., Kalamazm, Mich.. for the generous supplies of tolbutamide. One of the authors (P. M.) gratefully acknowledges the financial support of the Delegation Generale Recherche Sciences et Techniques (Paris, France).

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A high-performance liquid chromatographi
A high-performance liquid chromatographic method for the determination of nicardipine in plasma and its application to pharmacokinetics in humans
โœ Ke Li; Xin Zhang; Yi-sheng Yuan; Fei-lang Zhao ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 55 KB ๐Ÿ‘ 2 views

A simple and sensitive reversed-phase liquid chromatographic method has been developed and validated for the analysis of nicardipine in human plasma and the study of the pharmacokinetics of the drug in human body. Nicardipine and nimodipine (internal standard) in plasma were extracted with hexane-bu