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Method development strategies for the enantioseparation of drugs by capillary electrophoresis using cyclodextrins as chiral additives

✍ Scribed by Marianne Fillet; Philippe Hubert; Prof. Jacques Crommen


Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
692 KB
Volume
19
Category
Article
ISSN
0173-0835

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✦ Synopsis


Method development strategies for the enantioseparation of drugs by capillary electrophoresis using cyclodextrins as chiral additives


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Enantioseparation of thalidomide and its hydroxylated metabolites using capillary electrophoresis with various cyclodextrins and their combinations as chiral buffer additives The separation of thalidomide (TD) and its hydroxylated metabolites including their simultaneous enantioseparation was studi