Method development strategies for the enantioseparation of drugs by capillary electrophoresis using cyclodextrins as chiral additives
β Scribed by Marianne Fillet; Philippe Hubert; Prof. Jacques Crommen
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 692 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0173-0835
No coin nor oath required. For personal study only.
β¦ Synopsis
Method development strategies for the enantioseparation of drugs by capillary electrophoresis using cyclodextrins as chiral additives
π SIMILAR VOLUMES
## Abstract The influence of seven differently methylated Ξ²βcyclodextrin derivatives and of pure Ξ²βcyclodextrin (Ξ²βCD) on the enantiomeric resolution by capillary electrophoresis of six basic chiral pharmaceuticals is investigated. The methyl substitution pattern affects enantioselectivity much mor
Enantioseparation of thalidomide and its hydroxylated metabolites using capillary electrophoresis with various cyclodextrins and their combinations as chiral buffer additives The separation of thalidomide (TD) and its hydroxylated metabolites including their simultaneous enantioseparation was studi