METHIONINE REQUIREMENT IN SKIN FIBROBLASTS OF HUMANS WITH POLYPOSIS OF THE COLON AND THE GARDNER SYNDROME
β Scribed by Yves B. Mikol; Martin Lipkin
- Book ID
- 118720284
- Publisher
- John Wiley and Sons
- Year
- 1982
- Tongue
- English
- Weight
- 130 KB
- Volume
- 397
- Category
- Article
- ISSN
- 0890-6564
No coin nor oath required. For personal study only.
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## Abstract Chemical transformation of cultured human skin fibroblasts (PF) derived from individuals with hereditary adenomatosis of the colon and rectum is reported. Cells treated only with various levels of NβmethylβNβ²βnitroβNβnitrosoguanidine (MNNG) underwent morphological alteration. The morpho
## Abstract A heritable propensity to develop malignant lesions is found in individuals with familial adenomatosis of the colon and rectum (ACR) and the Gardner's syndrome variant, an autosomal dominant trait. In the present study, the growth characteristics of cultured skin fibroblasts (SF) derive