Methionine anchoring applied to the solid-phase synthesis of lysine-containing ‘head-to-tail’ cyclic peptides
✍ Scribed by Joseph C. Kappel; George Barany
- Publisher
- Springer Netherlands
- Year
- 2003
- Tongue
- English
- Weight
- 588 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1573-3149
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
An efficient and generally applicable method for the synthesis of head-to-tail cyclic peptides with HBTU (2-( lHbenzotriazol-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate) has been developed. The utility of this approach was exemplified with the multigram preparation of a potent endothelin re
Head-to-tail histidine containing cyclopeptides can be efficiently synthesised by a three-dimensional orthogonal solid-phase strategy (Fmoc/tBu/allyl) v/a anchoring the imidazole ring to trityi-resins. Furthermore, Fmoc-His(Trt-®)-OAl can be a useful starting support for the preparation of diketopip