𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Metal versus silyl triflate catalysis in the Mukaiyama aldol addition reaction

✍ Scribed by Erick M. Carreira; Robert A. Singer

Book ID
104214562
Publisher
Elsevier Science
Year
1994
Tongue
French
Weight
416 KB
Volume
35
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis

Abstra& A mechanistic study of the Mukaiyama aldol addition reaction employing benxaldehyde and hydtocinnamaldehyde along with a selection of Lewis acids including BF3aEt3, LiC104, Yb(OTf)3. Sn(OTfh, and Zn(OTfj2 is presented. The results of experiments conducted with doubly-labeled silyl ketene acetals implicate a Lewis acidic silicon species and not the metals as the catalyst in the Mukaiyama aldol addition reaction.

πŸ“œ SIMILAR VOLUMES

ChemInform Abstract: Functionalized Tria
ChemInform Abstract: Functionalized Triarylcarbenium Ions as Catalysts in Mukaiyama Aldol Addition: Effects of Counter Ions and Silyl Groups on the Intervention of Silyl Catalysis.
✍ C.-T. CHEN; S.-D. CHAO; K.-C. YEN πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 37 KB πŸ‘ 1 views

Functionalized Triarylcarbenium Ions as Catalysts in Mukaiyama Aldol Addition: Effects of Counter Ions and Silyl Groups on the Intervention of Silyl Catalysis. -It is documented, that a functionalized Tr + SbCl -6 [cf. (I)] may serve as catalyst in Mukaiyama aldol additions. The process highly depen

Auxiliary structure and asymmetric induc
Auxiliary structure and asymmetric induction in the β€œMukaiyama-aldol” reactions of chiral silyl ketene acetals
✍ Cesare Gennari; Francesco Molinari; PierGiorgio Cozzi; Ambrogio Oliva πŸ“‚ Article πŸ“… 1989 πŸ› Elsevier Science 🌐 French βš– 244 KB

## A variety of chiral auxiliaries R*OH were prepared ana' tested for levels of asymmetric induction control in the 'Mukaiyama-ala'& reaction of chiral siiyl ketene acetals. Structural features required for high levels of control are discussed.