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Metal inhibition of human N-methylpurine-DNA glycosylase activity in base excision repair

✍ Scribed by Ping Wang; Anton B. Guliaev; Bo Hang

Book ID
119378705
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
511 KB
Volume
166
Category
Article
ISSN
0378-4274

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## Abstract Primary astrocyte cultures were used to investigate the modulation of DNA repair as a tool for sensitizing astrocytes to genotoxic agents. Base excision repair (BER) is the principal mechanism by which mammalian cells repair alkylation damage to DNA and involves the processing of relati