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METACHRONOUS COLORECTAL AND BILIARY CARCINOMA: THE AETIOLOGICAL IMPLICATIONS OF K-RAS ONCOGENES

โœ Scribed by A. J. Spillane; J. M. Ham; C. L-S. Fung


Book ID
115182810
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
654 KB
Volume
66
Category
Article
ISSN
1445-1433

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## BACKGROUND. The majority of colorectal carcinomas, if not all, arise from a benign adenoma. The DNA of the carcinomatous cells frequently has mutations in several genes. However, it is not exactly clear when during the neoplastic process each mutation develops. An adenoma with an area of in sit