Metabolism of vitamin D3 in human osteoblasts: Evidence for autocrine and paracrine activities of 1α,25-dihydroxyvitamin D3
✍ Scribed by Gerald J. Atkins; Paul H. Anderson; David M. Findlay; Katie J. Welldon; Cristina Vincent; Andrew C.W. Zannettino; Peter D. O'Loughlin; Howard A. Morris
- Book ID
- 116319996
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 601 KB
- Volume
- 40
- Category
- Article
- ISSN
- 8756-3282
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## Abstract The differentiating and antitumor activities of 1α,25‐dihydroxyvitamin D~3~ (1α,25(OH)~2~D~3~) in vitro and 1α‐hydroxyvitamin D~3~ (1α(OH)D~3~) in vivo were studied with a human osteosarcoma cell line (OST strain). Antitumor activity was estimated with the use of 3‐(4,5‐dimethylthiazol)