𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Metabolic products of microorganisms

✍ Scribed by K. Uchida; H. Zähner

Publisher
Springer
Year
1976
Tongue
English
Weight
496 KB
Volume
107
Category
Article
ISSN
0302-8933

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✦ Synopsis

Rinamycin interfered with DNA-polymerase I of Escherichia coli in cell-free systems more effectively than actinomycin C. Its inhibitory action could be relieved by increasing the concentration of polymerase. The rinamycin concentrations that caused effective inhibition of the RNA-polymerase reaction in vitro were approximately 10 times higher than those required to inhibit the DNA-polymerase reaction in vitro.

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