𝔖 Bobbio Scriptorium
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Metabolic products of microorganisms

✍ Scribed by G. U. Brillinger; W. Heberle; B. Weber; H. Achenbach


Publisher
Springer
Year
1978
Tongue
English
Weight
600 KB
Volume
116
Category
Article
ISSN
0302-8933

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✦ Synopsis


In the course of a screening for new metabolites from fungi we isolated a substance with antimicrobial activity from cultures of Aspergillus duricaulis (CBS 481.65) (TΓΌ 679). It was antagonized by putrescine, spermidine, spermine, arginine, citrulline, lysine, ornithine, in higher concentration by aspraagine and glutamine too. The effect of ethylenediaminetetraacetate on the susceptibility of Streptomyces viridochromogenes (TΓΌ 57) and Bacillus subtilis ATCC 6051 to this antibiotic has been studied. The substance was characterized and identified as cyclopaldic acid.


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