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Metabolic normalization of α-ketoglutarate against N-nitrosodiethylamine-induced hepatocarcinogenesis in rats

✍ Scribed by K.B. Dakshayani; P. Subramanian; T. Manivasagam; M. Mohamed Essa


Book ID
111194351
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
64 KB
Volume
20
Category
Article
ISSN
0767-3981

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## Abstract The chemopreventive/chemotherapeutic effect of sodium selenite on tricarboxylic acid cycle key enzymes was investigated against hepatoma induced by environmental carcinogen N‐nitrosodiethylamine. Decreased activities of TCA cycle key enzymes such as isocitrate dehydrogenase (ICDH), succ