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Chemopreventive evaluation of Tephrosia purpurea against N-nitrosodiethylamine-induced hepatocarcinogenesis in Wistar rats

✍ Scribed by Talib Hussain; Hefazat H. Siddiqui; Sheeba Fareed; Madhavan Vijayakumar; Chandana Venkateswara Rao


Book ID
114983348
Publisher
Pharmaceutical Press
Year
2012
Tongue
English
Weight
815 KB
Volume
64
Category
Article
ISSN
2042-7158

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## Abstract The chemopreventive/chemotherapeutic effect of sodium selenite on tricarboxylic acid cycle key enzymes was investigated against hepatoma induced by environmental carcinogen N‐nitrosodiethylamine. Decreased activities of TCA cycle key enzymes such as isocitrate dehydrogenase (ICDH), succ