✦ LIBER ✦

Metabolic activation of the organophosphorus insecticides chlorpyrifos and fenitrothion by perfused rat liver

✍ Scribed by Lester G. Sultatos

Publisher: Elsevier Science
Year: 1991
Tongue: English
Weight: 470 KB
Volume: 68
Category: Article
ISSN: 0300-483X
DOI: 10.1016/0300-483x(91)90057-8

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Metabolic effects of p-coumaric acid in

Metabolic effects of p-coumaric acid in the perfused rat liver

✍ Leonardo C.N. Lima; Gisele D. Buss; Emy L. Ishii-Iwamoto; Clairce Salgueiro-Paga 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 165 KB 👁 1 views

## Abstract The __p__‐coumaric acid, a phenolic acid, occurs in several plant species and, consequently, in many foods and beverages of vegetable origin. Its antioxidant activity is well documented, but there is also a single report about an inhibitory action on the monocarboxylate carrier, which o

Metabolic effects of acetaminophen. Stud

Metabolic effects of acetaminophen. Studies in the isolated perfused rat liver

✍ Ana Maria Itinose; Marlene Leiko Doi Sakuno; Adelar Bracht 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 989 KB

The effects of acetaminophen on the metabolism of the isolated perfused rat liver were investigated. The following results were obtained: (1) Acetaminophen increased glucose release and glycolysis from endogenous glycogen (glycogenolysis). (2) Oxygen uptake, gluconeogenesis from either pyruvate or

Suppression of Lymphocyte Activation by

Suppression of Lymphocyte Activation by a Protein Released from Isolated Perfused Rat Liver

✍ Christopher Pizzo; Donald Lee; Francis V. Chisari 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 1023 KB

Isolated rat liver perfusates contain a substance which inhibits 3H-thymidine uptake by phytohemagglutinin-stimulated human peripheral blood lymphocytes in a dose-dependent, noncytotoxic fashion. Suppression is not due to interference of lymphocyte-phytohemagglutinin interaction or dilution of the t

Transport, metabolism and distribution s

Transport, metabolism and distribution space of octanoate in the perfused rat liver

✍ Osvaldo Ferraresi-Filho; Emy L. Ishii-Iwamoto; Adelar Bracht 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 213 KB 👁 2 views

The scope of the present work was to investigate the metabolism and the passage of octanoate from albumin into the phospholipid bilayer of the plasma membrane and from thence into the cell space. The experiments were done in the isolated perfused rat liver with infusions of albumin and octanoate at

Metabolism of 14C-2′,3′-dideoxyinosine b

Metabolism of 14C-2′,3′-dideoxyinosine by the in situ perfused rat liver preparation

✍ Lee K. Tay; Eugene A. Papp; Julita Timoszyk 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 590 KB

The metabolism and biliary excretion of i4C-dideoxyinosine (I4C-ddI) has been investigated using the in situ perfused rat liver (PRL) preparation. After 2 h of perfusion through the liver, approximately 7&75 per cent of the total I4C-radiolabel was recovered in the perfusion medium, less than 1 per

Hepatic extraction, metabolism, and bili

Hepatic extraction, metabolism, and biliary excretion of irinotecan in the isolated perfused rat liver

✍ Christian Farabos; Marie-Christine Haaz; Pierre Gires; Jacques Robert 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 199 KB 👁 2 views

Irinotecan (CPT-11) is a semisynthetic derivative of camptothecine that has proved activity in the treatment of colorectal carcinoma. The metabolites identi®ed in humans include SN-38, SN-38 glucuronide, and several CYP3A-derived metabolites. We have studied the hepatic extraction, metabolism, and b