## Abstract Diethylstilbestrol (DES) is a human carcinogen, based on sufficient epidemiological evidence. DES is mainly metabolized to its catechol, 3β²βhydroxyDES (3β²βOHβDES), which can further oxidize to DESβ3β²,4β²βquinone (DESβ3β²,4β²βQ). Similarly to estradiolβ3,4βquinone, the reaction of DESβ3β²,4β²
β¦ LIBER β¦
Metabolic Activation and Formation of DNA Adducts of Hexestrol, a Synthetic Nonsteroidal Carcinogenic Estrogen
β Scribed by Jan, Shyi-Tai; Devanesan, Prabu D.; Stack, Douglas E.; Ramanathan, Ragulan; Byun, Jaeman; Gross, Michael L.; Rogan, Eleanor G.; Cavalieri, Ercole L.
- Book ID
- 118178589
- Publisher
- American Chemical Society
- Year
- 1998
- Tongue
- English
- Weight
- 110 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0893-228X
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