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Metabolic Activation of Aflatoxin B 1 : Patterns of DNA Adduct Formation, Removal, and Excretion in Relation to Carcinogenesis

โœ Scribed by Essigmann, John M.; Croy, Robert G.; Bennett, Richard A.; Wogan, Gerald N.

Book ID
120984080
Publisher
Informa plc
Year
1982
Tongue
English
Weight
914 KB
Volume
13
Category
Article
ISSN
0360-2532

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โœ Rene E. Sotomayor; Saura Sahu; Melissa Washington; Dennis M. Hinton; Ming Chou ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 176 KB ๐Ÿ‘ 2 views

Fisher-344 male rats were fed 1.6 ppm of aflatoxin B 1 (AFB 1 ) continuously and intermittently for several weeks. At various time periods, DNA was isolated from the testes and livers and analyzed for AFB 1 -DNA adducts. The ability of the testis to detoxify AFB 1 was also investigated by the glutat