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Metabolic activation of benzo[a]pyrene in two fetal mouse hepatocyte lines: induction of DNA adducts and micronuclei

✍ Scribed by S. Canova; C. Viezzer; P. Venier; L. Navazio; R. Revoltella; L. Celotti


Book ID
116098489
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
548 KB
Volume
367
Category
Article
ISSN
0165-1218

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The aim of this study was to determine whether the micronucleus test, using the larvae of a lower invertebrate, the newt Pleurodeles waltl, is suitable for evaluating the overall genotoxicity of polluted water (AFNOR Standard, 1992). The study used the pollutant model benzo(a)pyrene (BaP). After hav