Mesenchymal change in the development of drug resistance in human neuroblastoma cells: A systems biology approach
โ Scribed by Jessica Ann Naiditch; Chunfa Jie; Timothy B. Lautz; Sandra Clark; Yi-Yong Qiu; Jafari Nadereh; Fei Chu; Mary Beth Madonna
- Book ID
- 118469124
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 57 KB
- Volume
- 215
- Category
- Article
- ISSN
- 1072-7515
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## Abstract Conditions are described for the development of methotrexate resistance in CCRF/CEM human lymphoid cells and an attempt is made to distinguish between those conditions that lead to methotrexate resistance through impairment of cellular transport of methotrexate and those that lead to re