Merrifield, Alpha-MethoxyPhenyl (MAMP) resin; a new versatile solid support for the synthesis of secondary amides
β Scribed by Dearg S. Brown; John M. Revill; Richard E. Shute
- Book ID
- 108387124
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- French
- Weight
- 225 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
A novel linker for the solid-phase synthesis of secondary amines based on an intramolecular cyclization was developed. The linker allows for a stepwise built-up of the secondary amines on the support. The feasibility was demonstrated in the parallel synthesis of a small set of different secondary am
A new and simple linker has been developed for synthesis of secondary amides and sulfonamides. This application is based on the reductive amination reaction between the acetophenone subunit of the linker and a wide range of primary amines including aliphatic and aromatic amines. Cleavage is effected