## Abstract ## Background. Controversy exists regarding the optimal management of patients with Merkel cell carcinoma. The primary aim of this study was to determine whether combined treatment with surgery and radiotherapy improves outcome in a multiβinstitutional cohort of patients with Merkel ce
Merkel cell carcinoma of the head and neck: A retrospective case series
β Scribed by Anthony E. Brissett; Kerry D. Olsen; Jan L. Kasperbauer; Jean E. Lewis; John R. Goellner; Bruce E. Spotts; Amy L. Weaver; Scott E. Strome
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 117 KB
- Volume
- 24
- Category
- Article
- ISSN
- 1043-3074
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
Background.
Eightyβfive percent of all Merkel cell carcinomas appear on sunβexposed areas, with 50% to 55% occurring on the head and neck.
Methods.
A chart review was performed on 22 patients treated for Merkel cell carcinoma of the head and neck between 1981 and 1998.
Results.
Fifteen patients were men (68%). The average age at operation was 69.9 years (range, 24β84 years). The average duration of followβup was 3.6 years (range, 3 daysβ8.6 years). Overall survival at 1, 2, and 3 years postoperatively was 78%, 68%, and 68%, respectively. The only independent predictor of survival was the type of surgical therapy. All patients who underwent wide local excision (WLE) of the primary tumor with dissection of the lymphatic drainage basin were alive at 2 years as opposed to 68% who had WLE alone and 33% who had Mohs surgery.
Conclusions.
WLE and dissection of the lymphatic drainage basin provided the best overall survival. Β© 2002 Wiley Periodicals, Inc. Head Neck 24: 982β988, 2002
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