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Membrane topology distinguishes a subfamily of the ATP-binding cassette (ABC) transporters

✍ Scribed by Gábor E Tusnády; Éva Bakos; András Váradi; Balázs Sarkadi

Book ID
117106990
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
445 KB
Volume
402
Category
Article
ISSN
0014-5793

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Active drug efflux transporters of the ATP binding cassette (ABC)-containing family of proteins have a major impact on the pharmacological behavior of most of the drugs in use today. Pharmacological properties affected by ABC transporters include the oral bioavailability, hepatobiliary, direct intes