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Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview

✍ Scribed by Alfred H Schinkel; Johan W Jonker


Book ID
114176140
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
459 KB
Volume
55
Category
Article
ISSN
0169-409X

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Mammalian drug efflux transporters of th
✍ Alfred H Schinkel; Johan W Jonker πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 English βš– 459 KB

Active drug efflux transporters of the ATP binding cassette (ABC)-containing family of proteins have a major impact on the pharmacological behavior of most of the drugs in use today. Pharmacological properties affected by ABC transporters include the oral bioavailability, hepatobiliary, direct intes