Mammalian drug efflux transporters of th
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Alfred H Schinkel; Johan W Jonker
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Article
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2003
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Elsevier Science
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English
β 459 KB
Active drug efflux transporters of the ATP binding cassette (ABC)-containing family of proteins have a major impact on the pharmacological behavior of most of the drugs in use today. Pharmacological properties affected by ABC transporters include the oral bioavailability, hepatobiliary, direct intes