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Membrane Differences in Peripheral Blood Lymphocytes from Patients with Chronic Lymphocytic Leukemia and Hodgkin's Disease

✍ Scribed by Uri Mintz and Leo Sachs

Book ID
123653281
Publisher
National Academy of Sciences
Year
1975
Tongue
English
Weight
766 KB
Volume
72
Category
Article
ISSN
0027-8424

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Changes in the surface membrane of lymph
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## Abstract Lymphocytes were isolated from the peripheral blood of 15 normal persons, 15 patients with chronic lymphocytic leukemia (CLL), 10 patients with Hodgkin's disease and 3 patients with CLL in remission. The cells were studied for cap formation and agglutinability by concanavalin A, and for

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We describe the presence of a high frequency of spontaneous chromosome aberrations in lymphocytes from six untreated patients with Hodgkin's disease. The characteristics of the chromosome abnormalities observed suggest the existence of a certain degree of chromosome instability in these cases, that