Cyclic AMP metabolism in peripheral blood lymphocytes from patients with Hodgkin's disease
β Scribed by Akolkar, Pradip N.; Advani, Suresh H.; Gothoskar, Balwant P.
- Book ID
- 122604899
- Publisher
- Elsevier Science
- Year
- 1984
- Weight
- 416 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0277-5379
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
We describe the presence of a high frequency of spontaneous chromosome aberrations in lymphocytes from six untreated patients with Hodgkin's disease. The characteristics of the chromosome abnormalities observed suggest the existence of a certain degree of chromosome instability in these cases, that
Peripheral blood lymphocytes from six untreated patients with Hodgkin's disease were exposed to various doses of ionizing radiation in vitro and thereafter tested for reactivity to PHA and ConA using DNA synthesis as a marker of viability. While the responsiveness of Hodgkin's disease lymphocytes wa