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Chromosome abnormalities in peripheral blood lymphocytes from untreated Hodgkin's patients

✍ Scribed by Leonardo Barrios; María Rosa Caballín; Rosa Mirò; Carme Fuster; Georgina Berrozpe; Antoni Subías; Xavier Batlle; Josep Egozcue

Publisher
Springer
Year
1988
Tongue
English
Weight
1003 KB
Volume
78
Category
Article
ISSN
0340-6717

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✦ Synopsis

We describe the presence of a high frequency of spontaneous chromosome aberrations in lymphocytes from six untreated patients with Hodgkin's disease. The characteristics of the chromosome abnormalities observed suggest the existence of a certain degree of chromosome instability in these cases, that could be a predisposing factor for the development of malignancies.

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