Conditioned media from cultures of human metastatic Hs294T melanoma cells contain a factor/facton that promote(s) fibroblast-mediated contraction of collagen lattices, and stimulate(s) fibroblast glycosaminoglycan (GAG) synthesis. Complete medium from melanoma cell cultures stimulated fibroblast hya
✦ LIBER ✦
Melanoma cell-derived factor stimulation of fibroblast glycosaminoglycan synthesis—The role of platelet-derived growth factor
✍ Scribed by J.L Godden; M Edward; R.M MacKie
- Book ID
- 117666096
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 258 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0959-8049
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## Background: Various tumours exhibit glycosaminoglycan rich, and in particular hyaluronan rich matrices surrounding them that facilitate tumour growth and invasion. in many tumours, this matrix is predominantly synthesized by fibroblasts following stimulation by tumour cell-derived factors. ## O